In this report, it will discuss digital transformation and change management on five key industries Retail, Manufacturing,Finance, Technology and Healthcare. Even though digital transformation is commonly related to the adoption of newadvancedtechnologies, such as AI, cloud computing, data analytics, and others, this paper is more concerned about the significanceoforganizational preparedness, its support by the leadership, and the role of employees in its successful implementation. Thereportseparates out how each sector is going about incorporating digital tools into work, investing in their resources, retrainingtheirpersonnel, and adjusting to culture based on a comparative thematic analysis using sector-specific data. Statistics alsoreveal thatTechnology and Finance industries are the most effective in terms of transformation due to good commitment of leadership, moreinvestment and adaptive cultures in the organization. The encounters in Retail and Healthcare are ambivalent, and inmost cases,split systems have been encountered or law restrictions put in place. Manufacturing, on the other hand, is not well preparedandresistant to change. The research article does not see the point of thinking that digital transformation is an activity whichisjusttechnical; it is a human based activity which requires a serious change management practice. The necessity to addressgeneralproblems and deliver quicker digital maturity entails cross sector instruction and designs. The report is currently useful totheleaders who wish to situate the digital innovation, along with the organization capacity and the long-termsuccess, as thereportidentifies both similarities and differences between the industries. Keywords: Digital transformation, Change management, Sectoral analysis, Organizational readiness, Technologyadoption,Leadership, Employee engagement, Digital maturity, Comparative study, Industry innovation