Electronic Health Records (EHRs) have become a fundamental component of modern healthcare systems byenablingefficient storage, management, and sharing of patient information across healthcare institutions. The rapid adoptionofcloudcomputing has significantly improved the accessibility, scalability, and availability of EHR systems while introducingcriticalchallenges related to data confidentiality, privacy preservation, authentication, access control, and secure informationsharing.This experimental study proposes a secure cloud-based Electronic Health Record Management framework that integratescloudcomputing technologies with encryption, authentication mechanisms, role-based access control, and secure communicationprotocols to enhance healthcare information security and system performance. The proposed framework incorporates healthcaredata preprocessing, secure cloud storage, user authentication, encrypted data transmission, access control management, andperformance evaluation into a unified computational architecture. A mathematical framework and algorithmic strategyaredeveloped to evaluate data security, resource utilization, response time, system reliability, and Quality of Service(QoS).Experimental evaluation demonstrates that cloud-based secure EHR management significantly improves informationconfidentiality, authentication accuracy, healthcare data availability, communication reliability, and computational efficiencywhile reducing unauthorized access and operational overhead. The proposed framework provides valuable guidanceforresearchers, healthcare organizations, cloud service providers, and healthcare information system developers seekingtodesignsecure, scalable, and reliable cloud-based electronic health record management systems. Keywords: Electronic Health Records, Cloud Computing, Healthcare Information Security, Secure Data Sharing, Access Control.