In this research we have analyzed structure with the different floor numbers for blast & seismic loading This researchpresents a detailed comparative study on the structural response of a 35-storey (G+34) reinforced concrete residential buildinganalyzed with and without seismic load combinations using STAAD Pro software. The building is modeled as a fixedjointedmulti-storey frame and analyzed as per relevant Indian Standards, including IS 456:2000, IS 875 (Parts 1–3), and IS 1893(Part 1):2002for Zone V seismic conditions. Structural parameters such as displacements, bending moments, shear forces, axial forcesareevaluated under different load combinations. The results indicate that the inclusion of seismic loads significantly increaseslateraldisplacement, axial forces in columns, and bending moments in beams, particularly in lower storeys and corner structuralmembers. Seismic load combinations govern the design of critical elements, leading to higher reinforcement requirementscompared to non-seismic cases. Keywords: Staad Pro, Axial Force, Displacement, Shear Force